5 Best Scalp Serums Approved by Dermatologists

A healthy scalp is the foundation for strong, vibrant hair. Dermatologists agree: if your scalp is dry, oily, or irritated, your hair cannot reach its full potential.

Scalp serums are lightweight, potent treatments formulated with active ingredients like peptides, biotin, salicylic acid, and botanical extracts to:

  • Promote scalp health

  • Reduce dryness or oiliness

  • Strengthen follicles

  • Support hair growth

Here are the 5 best dermatologist-approved scalp serums you need in your routine.

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5 Best Scalp Serums

The Ordinary Multi-Peptide Serum

Best for: Dry, sensitive scalps

What we love:

  • Hydrates & restores with hyaluronic acid and squalane

  • Lightweight, leave-in formula that won’t weigh hair down

  • Vegan, cruelty-free, silicone-free, alcohol-free, and gluten-free

  • Reduces dryness and itchiness while supporting the scalp barrier

How to use: Apply a few drops to clean, dry scalp once daily, ideally at bedtime. No rinsing needed.

The Inkey List Salicylic Acid Oily Scalp Treatment

Best for: Oily scalp and product buildup

What we love:

  • 7% Glycolic Acid gently exfoliates dead skin and unclogs follicles

  • Symcontrol® Scalp regulates sebum for a balanced scalp

  • Bioecolia® prebiotic supports scalp microbiome health

  • Alcohol, fragrance, sulfate, and gluten-free formula

  • Helps scalp feel fresh, light, and clean without over-drying

How to use: Pre-shampoo treatment 1–2 times per week for a clean, balanced scalp.

Act+Acre Cold Processed Stem Cell Scalp Serum

Best for: Thinning or shedding hair

What we love:

  • Apple stem cells + bamboo extract + aloe vera strengthen follicles

  • Moisturizes and soothes dryness and itchiness

  • Vegan, parabens & sulfates-free, color-safe

  • Clinically shown to improve hair thickness and density

  • Ideal for daily use on all hair types

How to use: Apply 1–2 pipettes to clean, damp or dry scalp daily. Massage in, leave-in.

Lanmeri Vegan Hair Growth Serum

Best for: Hair thinning & regrowth support

What we love:

  • 100% plant-based and cruelty-free

  • Combines peptides, amino acids, and phyto-actives to nourish follicles

  • Strengthens hair, reduces shedding, supports thicker, fuller growth

  • Clinically backed: up to 52% increase in hair density in 90 days

  • Lightweight, absorbs quickly, won’t leave hair greasy

How to use: Massage 1–2 pumps into scalp daily for best results.

Densifying & Thickening Serum for Thinning Hair

Best for: Thinning hair & hair density improvement

What we love:

  • Rootbiomic Ferment™ + densifying peptides + turmeric extract support follicle health

  • Targets all hair growth phases to improve density and thickness

  • Lightweight, non-greasy, safe for color-treated hair

  • Clinically shown: up to 85% reduction in hair fallout in 120 days

  • Perfect for daily use on crown, part line, and hairline

How to use: Apply 1–2 droppers to dry or towel-dried scalp daily, massage in, leave-in.

FAQ

1. Will scalp serums make my hair greasy?

Most serums are lightweight and leave-in, so they absorb quickly without leaving residue. Focus application on the scalp, not hair lengths, to avoid greasiness.

 

2. Can I use scalp serums on color-treated hair?

Yes! Many dermatologist-approved serums are color-safe, sulfate-free, and gentle, including Act+Acre, Lanmeri, and The Rootist. Always check labels if your scalp is sensitive.

 

3. How long until I see results from a scalp serum?

  • Dryness or irritation: often improves within days (The Ordinary)

  • Hair density or thickness: noticeable results may take 6–12 weeks (Lanmeri, The Rootist, Act+Acre)
    Consistency is key.

4. Can I use multiple serums at once?

It’s best to target your main scalp concern. Combining too many active ingredients may irritate the scalp. For example:

  • Hydration + dryness → The Ordinary

  • Hair thinning → Lanmeri or Act+Acre

5 Are scalp serums safe for sensitive scalps?

Yes! Most dermatologist-approved serums are free from parabens, sulfates, alcohol, and synthetic fragrances, making them suitable for sensitive scalps. Patch-test new products first to ensure compatibility.